persoanele care sufer\u0103<\/a> de TMAU, aceast\u0103 enzim\u0103 fie lipse\u0219te, fie func\u021bioneaz\u0103 defectuos, ceea ce duce la acumularea trimetilaminei \u00een organism. Aceasta este apoi eliminat\u0103 prin transpira\u021bie, urin\u0103 \u0219i respira\u021bie, gener\u00e2nd mirosul nepl\u0103cut.<\/p>\nCauzele TMAU pot fi:<\/p>\n
\u00a0 \u00a0 Muta\u021bii genetice \u2013 Majoritatea cazurilor sunt mo\u0219tenite, necesit\u00e2nd dou\u0103 copii defecte ale genei FMO3, una de la fiecare p\u0103rinte.<\/p>\n
\u00a0 \u00a0 Factori alimentari \u2013 Consumul excesiv de alimente care con\u021bin trimetilamin\u0103 poate agrava simptomele chiar \u0219i la persoanele cu o activitate enzimatic\u0103 normal\u0103.<\/p>\n
\u00a0 \u00a0 Afec\u021biuni hepatice \u2013 Insuficien\u021ba hepatic\u0103 poate influen\u021ba metabolizarea substan\u021bei.<\/p>\n
\u00a0 \u00a0 Dezechilibre hormonale \u2013 Femeile pot experimenta o agravare a simptomelor \u00een timpul ciclului menstrual, sarcinii sau menopauzei.<\/p>\n
Simptome \u0219i impact asupra s\u0103n\u0103t\u0103\u021bii mentale<\/p>\n
Trimetilaminuria poate debuta \u00eenc\u0103 de la na\u0219tere, \u00eens\u0103 simptomele devin evidente de obicei \u00een jurul pubert\u0103\u021bii, c\u00e2nd au loc schimb\u0103ri hormonale importante.<\/p>\n
Persoanele cu TMAU pot avea un miros persistent sau intermitent, influen\u021bat de diet\u0103, nivelul de stres sau transpira\u021bie. Aceast\u0103 problem\u0103 poate duce la izolare social\u0103, anxietate \u0219i depresie, afect\u00e2nd considerabil via\u021ba personal\u0103 \u0219i profesional\u0103.<\/p>\n
Exist\u0103 tratament pentru TMAU?<\/p>\n
De\u0219i nu exist\u0103 un remediu definitiv pentru TMAU, simptomele pot fi gestionate prin:<\/p>\n
\u00a0 \u00a0 Dieta controlat\u0103 \u2013 Evitarea alimentelor bogate \u00een trimetilamin\u0103 (pe\u0219te, ou\u0103, ficat, leguminoase) \u0219i a produselor lactate provenite de la vaci hr\u0103nite cu gr\u00e2u.<\/p>\n
\u00a0 \u00a0 Igien\u0103 strict\u0103 \u2013 Sp\u0103larea frecvent\u0103 a pielii \u0219i hainelor, utilizarea s\u0103punurilor u\u0219or acide \u0219i a antiperspirantelor.<\/p>\n
\u00a0 \u00a0 Reducerea transpira\u021biei \u2013 Limitarea exerci\u021biilor fizice intense \u0219i evitarea situa\u021biilor stresante.<\/p>\n
\u00a0 \u00a0 Tratament medicamentos \u2013 Administrarea de antibiotice \u00een doze mici pentru reducerea bacteriilor intestinale care produc trimetilamin\u0103 sau utilizarea c\u0103rbunelui activat, care poate \u00eempiedica absorb\u021bia acestei substan\u021be (cu precau\u021bia necesar\u0103, deoarece poate interac\u021biona cu alte medicamente).<\/p>\n
De\u0219i TMAU nu este periculoas\u0103 din punct de vedere medical, efectele sale psihologice \u0219i sociale sunt semnificative. Diagnosticul precoce \u0219i gestionarea corect\u0103 a simptomelor<\/a> pot \u00eembun\u0103t\u0103\u021bi considerabil via\u021ba pacien\u021bilor, ajut\u00e2ndu-i s\u0103 duc\u0103 o via\u021b\u0103 normal\u0103 \u00een ciuda provoc\u0103rilor impuse de aceast\u0103 afec\u021biune rar\u0103.<\/p>","protected":false},"excerpt":{"rendered":"Aceast\u0103 afec\u021biune afecteaz\u0103 mai frecvent femeile dec\u00e2t b\u0103rba\u021bii, iar cercet\u0103rile sugereaz\u0103 c\u0103 hormonii feminini, cum…<\/p>\n","protected":false},"author":0,"featured_media":43957,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[],"class_list":["post-43956","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-actual"],"_links":{"self":[{"href":"https:\/\/247stiri.ro\/index.php\/wp-json\/wp\/v2\/posts\/43956","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/247stiri.ro\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/247stiri.ro\/index.php\/wp-json\/wp\/v2\/types\/post"}],"replies":[{"embeddable":true,"href":"https:\/\/247stiri.ro\/index.php\/wp-json\/wp\/v2\/comments?post=43956"}],"version-history":[{"count":0,"href":"https:\/\/247stiri.ro\/index.php\/wp-json\/wp\/v2\/posts\/43956\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/247stiri.ro\/index.php\/wp-json\/wp\/v2\/media\/43957"}],"wp:attachment":[{"href":"https:\/\/247stiri.ro\/index.php\/wp-json\/wp\/v2\/media?parent=43956"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/247stiri.ro\/index.php\/wp-json\/wp\/v2\/categories?post=43956"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/247stiri.ro\/index.php\/wp-json\/wp\/v2\/tags?post=43956"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}